Development of Pentamidine Analogues as New Agents for the Treatment of Pneumocystis carinii Pneumonia
Identifieur interne : 003078 ( Main/Exploration ); précédent : 003077; suivant : 003079Development of Pentamidine Analogues as New Agents for the Treatment of Pneumocystis carinii Pneumonia
Auteurs : Richard R. Tidwell [États-Unis] ; Susan K. Jones [États-Unis] ; J. Dieter Geratz [États-Unis] ; Kwasi A. Ohemeng [États-Unis] ; Constance A. Bell [États-Unis] ; Bradley J. Berger [États-Unis] ; James Edwin Hall [États-Unis]Source :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 1990-12.
English descriptors
- Teeft :
- Adverse reactions, Agents chemother, Amidino group, Analogue, Antigiardial activity, Antiprotease activity, Aromatic rings, Assay, Butamidine, Carbon analogue, Carbon chain analogue, Carbon chain derivatives, Chain length, Compound, Compound xxiii, Compound xxvi, Control incubations, Daily dose, Derivative, Dose level, Dosing, Dosing regimen, Ether bond, Ether oxygens, Focal involvement, Good activity, Group histologic scores, Hilltop laboratories, Histologic, Histologic lung scores, Histologic score, Histologic scores, Hplc, Injection site, Isosteric replacement, Liver homogenate, Lung tissue, Mass spectrometry, Metabolic transformation, Methoxy groups, Myeloid cells, Oral dosing, Oral route, Parent compound, Parent molecule, Pentamidine, Pentamidine analogues, Pentamidine saline, Phase hplc, Position para, Score description, Score toxicity, Screening dose, Test compounds, Test dose, Test group, Tidwell, Toxic compounds, Toxicity, Urinary excretion, Xxiii, Xxvi, York academy.
Url:
DOI: 10.1111/j.1749-6632.1990.tb17862.x
Affiliations:
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